Mild Glucose Intolerance and Atherosclerosis in Aged Subjects

The role of apolipoprotein E and glucose intolerance in gallstone disease in middle aged subjects.

BACKGROUND The polymorphism of apolipoprotein E has been suggested to be associated with the cholesterol content of gallstones, the crystallisation rate of gall bladder bile, and the prevalence of gallstone disease (GSD). AIMS To investigate whether apolipoprotein E polymorphism modulates the susceptibility to GSD at the population level and to study the possible associations between impaired...

Postprandial triglyceridemia and carotid atherosclerosis in middle-aged subjects.

BACKGROUND AND PURPOSE It has been suggested that a postprandial accumulation of triglyceride-rich lipoproteins promotes the development of atherosclerosis. This study was designed to test the hypothesis that postprandial lipemia is independently associated with intima-media thickening of the extracranial carotid arteries. METHODS Forty-seven middle-aged, moderately hypercholesterolemic indiv...

Vibratory perception during ischaemia in uraemic patients and in subjects with mild carbohydrate intolerance.

Diabetic patients retain their vibratory perception during ischaemia longer than non-diabetics. This abnormality is found even in patients with newly diagnosed diabetes and it can be normalized after several days of intensive treatment with insulin (Steiness, 1959, 1961a; Gregersen, 1968a). Further studies in diabetics have demonstrated that the retained ability of nerve conduction during ischa...

Hyperinsulinemia and Glucose Intolerance

Diabetes and IGT Prevalence in Islamshahr and Detection of Glucose Intolerance Screening and GTT: A Comparison

SUMMARY Due to the lack of information on diabetes prevalence and its precipitating factors and in view of the grave consequences of the disease, this study was carried out in 1993 to determine diabetes and IGT in Islamshahr, 30 km to the southwest of Tehran. Out of 244000 population in the district 2033 subjects over 30 years of age were selected hy stepwise randomized sampling. The subjects ...